Process for producing a biomolecular monolayer on a surface, biosensor having a surface, and biochip

Described is a process for producing a biomolecular monolayer on a biosensor surface comprising the steps of: reacting a biosensor surface with a solution of heterobifunctional reagent having a first functional group and a second functional group, the first functional group being capable of forming...

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Bibliographische Detailangaben
Hauptverfasser: WOLF, HEIKO, AMONTOV, SERGEY, MICHEL, BRUNO, SWANSON, SALLY ANN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Described is a process for producing a biomolecular monolayer on a biosensor surface comprising the steps of: reacting a biosensor surface with a solution of heterobifunctional reagent having a first functional group and a second functional group, the first functional group being capable of forming a covalent bond to the biosensor surface groups, the second functional group forming a covalent bond with a homobifunctional polymer to obtain a self-assembled monolayer, and thereafter reacting the monolayer with capture molecules.