Method of performing rupture event scanning and transducer-based sensor system
A system and method for performing rupture event scanning and other sensing operations on a sample. The method includes providing (200) a transducer (20, 42, 44, 46, 48, 82, 84, 86, 88) with an immobilized binding partner material (22) and a sample material (24, 26) disposed thereon. The sample mate...
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Sprache: | eng |
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Zusammenfassung: | A system and method for performing rupture event scanning and other sensing operations on a sample. The method includes providing (200) a transducer (20, 42, 44, 46, 48, 82, 84, 86, 88) with an immobilized binding partner material (22) and a sample material (24, 26) disposed thereon. The sample material (24, 26) is applied to the immobilized binding partner material (22) so that, if components (26) in the sample material (24, 26) have sufficient affinity for the immobilized binding partner material (22), bonds will form between at least some of such components (26) and the immobilized binding partner material (22). The method further includes accelerating (204) the transducer (20, 42, 44, 46, 48, 82, 84, 86, 88) to induce bond breakage, where such accelerating is performed by applying a drive signal (130, 132, 134, 136) to the transducer (20, 42, 44, 46, 48, 82, 84, 86, 88). The drive signal (130, 132, 134, 136) includes a waveform (130, 132, 134, 136) having multiple frequency components that are pre-selected based on expected resonance behavior of the transducer (20, 42, 44, 46, 48, 82, 84, 86, 88). The method may also include analyzing an output response of the transducer (20, 42, 44, 46, 48, 82, 84, 86, 88) in response to application of the drive signal (130, 132, 134, 136). |
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