Tricycle indolyl compound with affinity of the serotonin-receptor

Tricycle indolyl compound with affinity of the serotonin-receptor

The following compound (I) possesses the affinity of serotonin-receptor, which is effective to be medicine of any treatment of the central nervous system, (wherein R1 represents hydrogen; R2 represents hydrogen or lower alkyl group; R3 represents hydrogen, -CCOR12 etc.; R4 represents hydrogen, lower...

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Bibliographische Detailangaben
Hauptverfasser: ADACHI, MAKOTO, FUKUI, YOSHIKAZU, SASATANI, TAKASHI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The following compound (I) possesses the affinity of serotonin-receptor, which is effective to be medicine of any treatment of the central nervous system, (wherein R1 represents hydrogen; R2 represents hydrogen or lower alkyl group; R3 represents hydrogen, -CCOR12 etc.; R4 represents hydrogen, lower alkyl group etc., or R3 and R4 conjugately form =0 or =S; R5 represents hydrogen, or R3 and R5 conjugately form a single bond; R6 represents hydrogen, -COOR24 etc.; R7 represents hydrogen, halogen, lower alkyl group, etc.; R8 represents hydrogen, halogen, cyclic alkyl group, etc.; R9, R10 and R11 individually represent hydrogen, halogen, lower alkyl group, etc.)