Aryl carboxylic acid and tetrazole derivatives

Aryl carboxylic acid and tetrazole derivatives

This invention relates to compounds which are generally IP receptor modulators, particularly IP receptor agonists, and which are represented by formula I, wherein R1, R2, R3, R4, R5, A, and B are as defined in the specification, and individual isomers, racemic or non-racemic mixtures of isomers, or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SEVERANCE, DANIEL LEE, LOPEZ-TAPIA, FRANCISCO JAVIER, O'YANG, COUNDE, MUEHLDORF, ALEXANDER VICTOR
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention relates to compounds which are generally IP receptor modulators, particularly IP receptor agonists, and which are represented by formula I, wherein R1, R2, R3, R4, R5, A, and B are as defined in the specification, and individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.