Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives

The present invention relates to novel positive cardiac inotropic and lusitropic compounds of formula (I), the pharmaceutical acceptable acid addition salts thereof and the stereochemically isomeric forms thereof wherein L is a radical of formula -O-Alk-(NH)p-C(=O)-R1, pharmaceutical compositions th...

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Hauptverfasser: FREYNE, EDDY J. E, RAEYMAEKERS, ALFONS H. M
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel positive cardiac inotropic and lusitropic compounds of formula (I), the pharmaceutical acceptable acid addition salts thereof and the stereochemically isomeric forms thereof wherein L is a radical of formula -O-Alk-(NH)p-C(=O)-R1, pharmaceutical compositions thereof, methods of preparing said compounds and intermediates in the preparation thereof.