Pharmaceutical compositions useful for inhibiting amyloid aggregation in a mammal
Amyloid aggregation in animals is inhibited by administering a 9-acridinone compound of the formula, wherein: R1 and R2 are hydrogen, halo, nitro, amino, hydroxy, trifluoromethyl, alkyl, alkoxy, and alkylthio; R3 is hydrogen or alkyl; and R4 is -alkylene-NR5R6. The compounds are especially useful in...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Amyloid aggregation in animals is inhibited by administering a 9-acridinone compound of the formula, wherein: R1 and R2 are hydrogen, halo, nitro, amino, hydroxy, trifluoromethyl, alkyl, alkoxy, and alkylthio; R3 is hydrogen or alkyl; and R4 is -alkylene-NR5R6. The compounds are especially useful in preventing and treating Alzheimer's disease. |
|---|