New polymorphic form of doxazosin mesylate (form II)
A new crystalline and anhydrous form of doxazosin mesylate is described. The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 10.68 DEG, 23.45 DEG, 14.45 DEG, 23.82 DEG, 17.37 DEG, 24.30 DEG. Owing to its...
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creator | MORSDORF, JOHANN PETER GRAFE, INGOMAR |
description | A new crystalline and anhydrous form of doxazosin mesylate is described. The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 10.68 DEG, 23.45 DEG, 14.45 DEG, 23.82 DEG, 17.37 DEG, 24.30 DEG. Owing to its crystalline properties, the new form of doxazosin mesylate according to the invention has surprising advantages both with regard to its synthesis and for pharmaceutical processing into solid dosage forms. A process for preparing the new form of doxazosin mesylate and medicaments containing the new form of doxazosin mesylate are also described. |
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The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 10.68 DEG, 23.45 DEG, 14.45 DEG, 23.82 DEG, 17.37 DEG, 24.30 DEG. Owing to its crystalline properties, the new form of doxazosin mesylate according to the invention has surprising advantages both with regard to its synthesis and for pharmaceutical processing into solid dosage forms. A process for preparing the new form of doxazosin mesylate and medicaments containing the new form of doxazosin mesylate are also described.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011201&DB=EPODOC&CC=TW&NR=466239B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011201&DB=EPODOC&CC=TW&NR=466239B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MORSDORF, JOHANN PETER</creatorcontrib><creatorcontrib>GRAFE, INGOMAR</creatorcontrib><title>New polymorphic form of doxazosin mesylate (form II)</title><description>A new crystalline and anhydrous form of doxazosin mesylate is described. 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A process for preparing the new form of doxazosin mesylate and medicaments containing the new form of doxazosin mesylate are also described.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDxSy1XKMjPqczNLyrIyExWSMsvylXIT1NIya9IrMovzsxTyE0trsxJLElV0ADLeXpq8jCwpiXmFKfyQmluBnk31xBnD93Ugvz41OKCxOTUvNSS-JBwEzMzI2NLJydjwioAZjYr0A</recordid><startdate>20011201</startdate><enddate>20011201</enddate><creator>MORSDORF, JOHANN PETER</creator><creator>GRAFE, INGOMAR</creator><scope>EVB</scope></search><sort><creationdate>20011201</creationdate><title>New polymorphic form of doxazosin mesylate (form II)</title><author>MORSDORF, JOHANN PETER ; GRAFE, INGOMAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_TW466239BB3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2001</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MORSDORF, JOHANN PETER</creatorcontrib><creatorcontrib>GRAFE, INGOMAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MORSDORF, JOHANN PETER</au><au>GRAFE, INGOMAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>New polymorphic form of doxazosin mesylate (form II)</title><date>2001-12-01</date><risdate>2001</risdate><abstract>A new crystalline and anhydrous form of doxazosin mesylate is described. The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 10.68 DEG, 23.45 DEG, 14.45 DEG, 23.82 DEG, 17.37 DEG, 24.30 DEG. Owing to its crystalline properties, the new form of doxazosin mesylate according to the invention has surprising advantages both with regard to its synthesis and for pharmaceutical processing into solid dosage forms. A process for preparing the new form of doxazosin mesylate and medicaments containing the new form of doxazosin mesylate are also described.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | New polymorphic form of doxazosin mesylate (form II) |
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