New polymorphic form of doxazosin mesylate (form II)

A new crystalline and anhydrous form of doxazosin mesylate is described. The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 10.68 DEG, 23.45 DEG, 14.45 DEG, 23.82 DEG, 17.37 DEG, 24.30 DEG. Owing to its...

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Hauptverfasser:	MORSDORF, JOHANN PETER, GRAFE, INGOMAR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A new crystalline and anhydrous form of doxazosin mesylate is described. The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 10.68 DEG, 23.45 DEG, 14.45 DEG, 23.82 DEG, 17.37 DEG, 24.30 DEG. Owing to its crystalline properties, the new form of doxazosin mesylate according to the invention has surprising advantages both with regard to its synthesis and for pharmaceutical processing into solid dosage forms. A process for preparing the new form of doxazosin mesylate and medicaments containing the new form of doxazosin mesylate are also described.