1-[ -(3,4-dihydro-2-naphthalenyl) alkyl] cyclic amine derivatives and processes for preparation thereof and pharmaceutical composition containing the same

A compound of formula (I) or salt and N-oxide derivatives, where R1 and R2, identical or different, represent H, halogen, hydroxy, C1-5 alkyl, C1-3 alkoxy, hydroxymethyl, formyl, carboxyl or C103 alkoxycarbonyl, or R1 and R2 and adjacent C together form methylenedioxy, -CH2CH2O-, trimethylene, tetra...

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Hauptverfasser: KAWASHIMA, KATSUYOSHI, NAOKI, KAI, HINO, KATUHIKO, KANEHIRA, AKI, ISAO SHIMIZU, MORIE, TOSHIYA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A compound of formula (I) or salt and N-oxide derivatives, where R1 and R2, identical or different, represent H, halogen, hydroxy, C1-5 alkyl, C1-3 alkoxy, hydroxymethyl, formyl, carboxyl or C103 alkoxycarbonyl, or R1 and R2 and adjacent C together form methylenedioxy, -CH2CH2O-, trimethylene, tetramethylene; R3 is H, halo, trifluoromethyl, C1-5 alkyl, C1-3 alkoxy or phenyl; R4 is H, halo, hydroxy, C1-3 alkyl or (C1-2 alkoxy) methyl; R5 is H, halo, C1-3 alkyl or (C1-2 alkoxy) methyl or R4 and R5 and adjacent C other than that connected with N together form an oxy; p is an integer of 2 to 6, q is an integer of 3 to 7, in the proviso where R1, R2, R3, R4 and R5 are all H, p is 2 and q is 5).