Engineered nerve grafts, methods of making the same, and methods of treatment using the same

The present disclosure provides engineered nerve grafts, methods of making engineered nerve grafts, and methods of using an engineered nerve graft to repair a nerve. Engineered nerve grafts of the present disclosure may include a body extending from a first end to a second end, the body being formed...

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Bibliographische Detailangaben
Hauptverfasser: AGRAWAL, NIKUNJ KUMAR, DEISTER, CURT
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present disclosure provides engineered nerve grafts, methods of making engineered nerve grafts, and methods of using an engineered nerve graft to repair a nerve. Engineered nerve grafts of the present disclosure may include a body extending from a first end to a second end, the body being formed of a biocompatible hydrogel, and a plurality of microchannels extending continuously through the body from the first end to the second end, wherein each of the plurality of microchannels may have an effective diameter of about 1 micrometer to about 200 micrometers.