Compounds that inhibit PKMYT1

Disclosed herein are compounds according to Formula I.. Compounds according to Formula I inhibit PKMYT1 and are useful for the treatment of cancer and other disease. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

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Bibliographische Detailangaben
Hauptverfasser: COLE, DAVID J, KELLEY, RYAN, LANSDOWN, RACHAEL, NG, DANNY, MAUNG, JACK, MAHANEY, PAIGE ERIN, ZHANG, BEIN, GILLESPIE, PAUL, LIN, XIAODONG, BANNEN, LYNNE, WANG, YONG, MA, SUNGHOON, SALVANT, JUSTIN, BOSWELL, BENJAMIN R, JIANG, FAMING, ZHAO, ZHEN-SHENG, WU, GUOSHENG, ST. AMANT, ANDRE H, XU, WEI, RAIKAR, SANDEEP N, PIPER, DEREK, RICO, ALICE C, PAYANDEH, JIAN MEHR-DEAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:Disclosed herein are compounds according to Formula I.. Compounds according to Formula I inhibit PKMYT1 and are useful for the treatment of cancer and other disease. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.