Saliva collection method and saliva collection member and method for determining absence/presence of bleeding and method for determining progress state of periodontal disease

Provided is a determination method with which it is possible to find a saliva collection member achieving simple and noninvasive collection, and by simply subjecting the collection member after saliva collection to centrifugal separation without any special treatment, occult blood in saliva can be d...

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Hauptverfasser: KOMINE, KENICHI, KOMINE, YUMIKO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided is a determination method with which it is possible to find a saliva collection member achieving simple and noninvasive collection, and by simply subjecting the collection member after saliva collection to centrifugal separation without any special treatment, occult blood in saliva can be determined and inflammatory-inducing lactoferrin polypeptide concentration in the saliva can be measured, enabling disease state classification of a periodontal disease in humans and animals. In this invention, saliva is noninvasively collected by selecting and using a nonwoven cloth capable of quantitatively collecting saliva. The nonwoven cloth after the collection is set to a filtration device to apply centrifugal separation. A blood component remaining on the nonwoven cloth after the centrifugal separation is visually observed to detect occult blood in the saliva. Moreover, by also measuring the I-Lf concentration in the liquid phase specimen after the centrifugal separation, it is possible to classify the condi