Mammalian cell line and method for expressing soluble E2 recombinant antigen of classical swine fever virus using the same and application thereof

The present invention relates to a mammalian cell line and a method for expressing soluble E2 recombinant antigen of classical swine fever virus using the same. The mammalian cell line with different cell passage numbers can stably express soluble CSFV-E2 recombinant protein in mass production, for...

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Hauptverfasser: CHUNG, WEN-BIN, CHEN, CHIIH, CHAUNG, HSOI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a mammalian cell line and a method for expressing soluble E2 recombinant antigen of classical swine fever virus using the same. The mammalian cell line with different cell passage numbers can stably express soluble CSFV-E2 recombinant protein in mass production, for reducing the manufacturing cost of the CSFV-E2 recombinant protein, as well as application on the production of a porcine CSFV-E2 subunit vaccine composition.