Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof

The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae ser...

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Hauptverfasser: MORAN, JUSTIN KEITH, GALLAGHER, CAITLYN, DUTTA, KAUSHIK, VARTAK, ABHISHEK RAVINDRA, ANDERSON, ANNALIESA SYBIL, KANEVSKY, ISIS, SINGH, SUDDHAM, YANG, YUYING, GU, JIANXIN, SURENDRAN, NAVEEN, ALEX, CATHERINE, KIM, JIN-HWAN, BHETUWAL, BISHWA RAJ, CHEN, ZECHENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in Prevnar, Synflorix and/or Prevnar 13. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumoccocal infections using said novel immunogenic compositions.