System and method for centering alignment of pick-up module capable of prevent centering errors of a pick-up module

The present invention provides a device and method for centering alignment of a pick-up module, which can prevent centering errors of the pick-up module. The centering alignment device for the pick-up module may include: an edge sensing device that senses a left edge, a right edge, a front edge and a rear edge of a chuck or a chuck-type fixture installed on a pick-up head; and a control unit that calculates the coordinates of the center point of the pick-up head using the edge sensing information sensed by the edge sensing device.