Photoreceptor rescue cell (PRC) compositions and methods for treatment of ocular disorders

The present invention provides populations of photoreceptor rescue cells (PRC) possessing unique marker profiles and generated by in vitro differentiation from earlier progenitors including pluripotent stem cells and embryonic stem cells (ESCs). Methods of generating the populations of photoreceptor...

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Bibliographische Detailangaben
Hauptverfasser: ABE, MASASHI, THERIAULT, KRAIG MARC, KIMBREL, ERIN, PODOLSKIY, DMITRIY I, PAULSEN, SAMANTHA JEAN, JO, REBECCA EUNKYUNG, LUO, CHENMEI, HILER, DANIEL JAMES, DAO, DANG QUY, REYES RAMIREZ, SANTIAGO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention provides populations of photoreceptor rescue cells (PRC) possessing unique marker profiles and generated by in vitro differentiation from earlier progenitors including pluripotent stem cells and embryonic stem cells (ESCs). Methods of generating the populations of photoreceptor rescue cells and using them for treatment of ocular disorders are also provided.