Formulations containing anti-TIGIT antibody and methods of use thereof

The present invention relates generally to the field of pharmaceutical formulations of antibodies against T cell immunoreceptor with Ig and ITIM domains (TIGIT), or antigen binding fragments thereof. The pharmaceutical formulations of the present invention exhibit a substantial degree of anti-TIGIT...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	GU, SU-FANG, JIN, XIAO-QING, JI, YU, QIU, BO, DI, AI-JUN, LI, JIN-MEI, XU, KAI, ZHANG, YUAN-YUAN, SHEN, JIAN, WU, JUN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates generally to the field of pharmaceutical formulations of antibodies against T cell immunoreceptor with Ig and ITIM domains (TIGIT), or antigen binding fragments thereof. The pharmaceutical formulations of the present invention exhibit a substantial degree of anti-TIGIT antibody stability after being subjected to stress conditions, accelerated and long-term storage. Also provided are methods of making and methods of using such antibody formulations.