Heterocyclic compound

The invention provides a compound of Formula (I), or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a hydrate thereof:, wherein X, Y, R1, R2, R3, R4, R5, and R6 are as defined in the specification, for treatment of a disease, disorder or condition associated with NLRP3, includi...

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Bibliographische Detailangaben
Hauptverfasser: TOITA, AKINORI, YUKAWA, TAKAFUMI, OHASHI, TOMOHIRO, DAINI, MASAKI, TANAKA, YUTA, HOMMA, MISAKI, NAKAMURA, SHINJI, WANG, CHUN-XIANG, HIDAKA, KOSUKE, ITO, MASAHIRO, IMAMURA, KEISUKE, MORIMOTO, SHINJI, KIKUCHI, FUMIAKI, UYGHUR, DILHUMAR, MIKAMI, SATOSHI, HASUI, TOMOAKI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a compound of Formula (I), or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a hydrate thereof:, wherein X, Y, R1, R2, R3, R4, R5, and R6 are as defined in the specification, for treatment of a disease, disorder or condition associated with NLRP3, including a disease, disorder or condition associated with a heterozygous gain of function mutation in the NLRP3 gene such as cryopyrin-associated periodic syndrome (CAPS).