Hydrogel composition including a cross-linked collagen polymer, a carboxymethyl cellulose derivative, an aqueous sodium chloride solution, a humectant and an antimicrobial agent

A hydrogel composition includes a cross-linked collagen polymer, a carboxymethyl cellulose derivative, an aqueous sodium chloride solution, a humectant and an antimicrobial agent. The crosslinked collagen polymer has collagen, hydrophilic polyether, and a dicarbamate group connecting the collagen to the hydrophilic polyether. The carboxymethyl cellulose derivative is selected from carboxymethyl cellulose, an alkali metal salt thereof an ammonium salt thereof, or a combination thereof. The humectant is selected from glycerin, propylene glycol or a combination thereof. The antimicrobial agent is a combination of betaine glycinate and polyhexamethylene bisguanidine hydrochloride. The hydrogel composition facilitates uniform absorption of exudate from a wound and encapsulation of the wound, has a perfect anti-inflammatory effect, and has a good antimicrobial activity, which in turn helps to increase the rate of healing the wound.