Composite formulation for oral dosage comprising 1-(3-cyano-1-isopropyl-indol-5-yl)pyrazol-4-carboxyl acid

The present invention relates to a composite formulation for oral dosage that comprises an API selected from 1-(3-cyano-1-isopropyl-indol-5-yl)pyrazol-4-carboxylic acid or a pharmaceutically acceptable salt thereof and does not comprise a pH modifier as an excipient. Since the composite formulation...

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Hauptverfasser: YOO, SEOKOL, KIM, REE-SUN, JANG, JOO-MYUNG, SEO, JIN-A
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a composite formulation for oral dosage that comprises an API selected from 1-(3-cyano-1-isopropyl-indol-5-yl)pyrazol-4-carboxylic acid or a pharmaceutically acceptable salt thereof and does not comprise a pH modifier as an excipient. Since the composite formulation for oral dosage according to the present invention does not comprise a pH modifier, it has the advantage of having a high level of dissolution rate as well as enhanced dosing convenience and productivity, in spite of comprising a high content of API.