Cannabinoid type 1 receptor binding proteins and uses thereof

Described herein are anti-CB1 (e.g., huCB1) antibodies and antigen binding fragments, compositions comprising the same and their use for the treatment of various disorders or diseases such as obesity and its comorbidities, chronic kidney disease, liver disease (e.g., NAFLD), and NASH.

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Bibliographische Detailangaben
Hauptverfasser: CHEN, IRWIN, PASUMARTHI, VENKATA NIHAL, MATOCHIKO, WADIM L, BERGEN, JOHN, CHONG, SU, LI, SERINA, OXENOID, KIRILL, VENIANT-ELLISON, MURIELLE MARIE, KILLION, ELIZABETH ANN, HAN, SEOG JOON, LU, SHUN, WEISHUHN, DAWN, CHEN, WEIHSU CLAIRE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Described herein are anti-CB1 (e.g., huCB1) antibodies and antigen binding fragments, compositions comprising the same and their use for the treatment of various disorders or diseases such as obesity and its comorbidities, chronic kidney disease, liver disease (e.g., NAFLD), and NASH.