Formulations for suprachoroidal administration such as formulations with aggregate formation

Provided herein are pharmaceutical compositions for administration to a suprachoroidal space of an eye of a subject. The pharmaceutical compositions can include a recombinant adeno-associated virus (AAV) encoding a transgene. Also provided herein are methods for treating or preventing a disease in a...

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Bibliographische Detailangaben
Hauptverfasser: MARSHALL, TRISTAN JAMES, BEE, JARED, BUDZYNSKI, EWA, BUSS, NICHOLAS ALEXANDER PIERS SASCHA, VAN EVEREN, SHERRI, PAKOLA, STEPHEN JOSEPH
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are pharmaceutical compositions for administration to a suprachoroidal space of an eye of a subject. The pharmaceutical compositions can include a recombinant adeno-associated virus (AAV) encoding a transgene. Also provided herein are methods for treating or preventing a disease in a subject by administering a therapeutically effective amount of the pharmaceutical compositions to the subject in need.