Activators of effector T cells

The present disclosure provides antibody drug conjugates and methods of delivering the conjugates to effector T cells. Also disclosed are novel Cbl-b inhibitors. The compounds and conjugates are useful for treating diseases in subjects in need thereof.

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Bibliographische Detailangaben
Hauptverfasser:	RIBKOVSKAIA, ZINAIDA, TAKROURI, KHULOUD, PARK, PETER U, FISHKIN, NATHAN, PALACINO, JAMES J, WONG, WESLEY, NAMGOONG, SUK, LIM, JOANNE Y. H, SKALETSKAYA, ANNA, BAI, CHEN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides antibody drug conjugates and methods of delivering the conjugates to effector T cells. Also disclosed are novel Cbl-b inhibitors. The compounds and conjugates are useful for treating diseases in subjects in need thereof.