Analytical method
A method for assessing the neutralizing potential of antibodies in a complex biological sample, the method comprising contacting the complex biological sample with a flow-based analytical device, the analytical device being provided with an antigen of interest, allowing antibodies present in the com...
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| Format: | Patent |
| Sprache: | chi ; eng |
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| Zusammenfassung: | A method for assessing the neutralizing potential of antibodies in a complex biological sample, the method comprising contacting the complex biological sample with a flow-based analytical device, the analytical device being provided with an antigen of interest, allowing antibodies present in the complex biological sample to interact with the antigen of interest, and determining the association-rate binding constant ka of the antibody-antigen interaction and/or the dissociation-rate binding constant kd of the antibody-antigen interaction. |
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