Multidose ophthalmic compositions
The present invention relates to aqueous cyclodextrin compositions containing drug/cyclodextrin complexes and sorbic acid or a pharmaceutically acceptable sorbate that exhibit a superior antimicrobial preservation effect at a low preservative concentration, and to an aqueous eye drop microsuspension...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The present invention relates to aqueous cyclodextrin compositions containing drug/cyclodextrin complexes and sorbic acid or a pharmaceutically acceptable sorbate that exhibit a superior antimicrobial preservation effect at a low preservative concentration, and to an aqueous eye drop microsuspension containing solid drug/cyclodextrin complexes and sorbic acid or a pharmaceutically acceptable sorbate, which is suitable as a multidose formulation. |
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