Multidose ophthalmic compositions

The present invention relates to aqueous cyclodextrin compositions containing drug/cyclodextrin complexes and sorbic acid or a pharmaceutically acceptable sorbate that exhibit a superior antimicrobial preservation effect at a low preservative concentration, and to an aqueous eye drop microsuspension...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LOFTSSON, THORSTEINN, PILOTAZ, FREDERIC
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to aqueous cyclodextrin compositions containing drug/cyclodextrin complexes and sorbic acid or a pharmaceutically acceptable sorbate that exhibit a superior antimicrobial preservation effect at a low preservative concentration, and to an aqueous eye drop microsuspension containing solid drug/cyclodextrin complexes and sorbic acid or a pharmaceutically acceptable sorbate, which is suitable as a multidose formulation.