Antigen binding polypeptide complexes containing extracellular domains of TNFSF ligands

Disclosed are antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptide complexes; cells, pharmaceutical compositions, and kits containing such polypeptid...

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Bibliographische Detailangaben
Hauptverfasser: SEUNG, EDWARD, YANG, ZHI-YONG, WEI, RONNIE R, ZERHOUNI, ELIAS, NABEL, GARY J, KAMP, HEATHER DAWN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Disclosed are antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptide complexes; cells, pharmaceutical compositions, and kits containing such polypeptide complexes; and methods of using such polypeptide complexes.