Process for preparing sartan active compounds having a tetrazole ring

The present disclosure relates to a process for manufacturing at least one sartan active compound of formula (I), wherein R is selected from a group of formulas (1), (2), (3), (4) and (5), comprising the tetrazolylation of one compound of formula (II), wherein R is as previously defined, in a reacti...

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Bibliographische Detailangaben
Hauptverfasser: GRIMAUD, BERNARD, GALIBOURG, ISABELLE, CRUCIANI, PAUL
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure relates to a process for manufacturing at least one sartan active compound of formula (I), wherein R is selected from a group of formulas (1), (2), (3), (4) and (5), comprising the tetrazolylation of one compound of formula (II), wherein R is as previously defined, in a reactional medium with at least one azide derivative, wherein benzylic azide impurities formed during said tetrazolylation are converted into aldehyde derivatives.