Inhibitors of HIF-2alpha and methods of use thereof

The present disclosure is directed to compounds that are inhibitors of HIF-2[alpha] having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.

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Bibliographische Detailangaben
Hauptverfasser:	YU, KAI, HARDMAN, CLAYTON, LAWSON, KENNETH VICTOR, EPPLIN, MATTHEW, BEATTY, JOEL WORLEY, DREW, SAMUEL LAWRIE, GAL, BALINT, POWERS, JAY PATRICK, LELETI, MANMOHAN REDDY, LIU, DONG-DONG, PODUNAVAC, MASA, FOURNIER, JEREMY, MATA, GUILLAUME, ROSEN, BRANDON REID, MAILYAN, ARTUR KARENOVICH
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure is directed to compounds that are inhibitors of HIF-2[alpha] having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.