Anti-epha4 antibody

To provide an antibody that can bind specifically to EphA4 and detect EphA4 at high detection sensitivity and a method and a kit for detecting or quantifying EphA4 characterized by the antibody. Provided are an antibody having a specific heavy chain CDR sequence and light chain CDR sequence and an a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHUTA, KAZUYOSHI, TAHARA, KAZUHIRO, KAWAKATSU, TOMOMI
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:To provide an antibody that can bind specifically to EphA4 and detect EphA4 at high detection sensitivity and a method and a kit for detecting or quantifying EphA4 characterized by the antibody. Provided are an antibody having a specific heavy chain CDR sequence and light chain CDR sequence and an antigen-binding fragment thereof, and a method and kit characterized by the same. Specifically, an antibody according to the present invention or antigen-binding fragment thereof includes: (a) a heavy chain including a heavy chain CDR1 comprising an amino acid sequence represented by SEQ ID NO: 52, a heavy chain CDR2 comprising an amino acid sequence represented by SEQ ID NO: 53, and a heavy chain CDR3 comprising an amino acid sequence represented by SEQ ID NO: 54, and a light chain including a light chain CDR1 comprising an amino acid sequence represented by SEQ ID NO: 55, a light chain CDR2 comprising an amino acid sequence represented by SEQ ID NO: 56, and a light chain CDR3 comprising an amino acid sequence repr