Intratumoral alpha-emitter radiation in combination with immune checkpoint regulators

A substance which regulates immune-checkpoints for use as a medicament for treatment of a tumor of a patient wherein the administration pattern of the medicament comprises administering a therapeutically effective amount of the substance to the tumor, in one or more sessions, and implanting seeds (2...

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Bibliographische Detailangaben
Hauptverfasser: DEN, ROBERT, SHAI, AMIT, ROUMANI, SARA DEL MARE, MANSOUR, FAIRUZ, KEISARI, YONA, NISHRI, YOSSI, SEGAL, RONEN, EFRATI, MARGALIT, DOMANKEVICH, VERED, KELSON, ITZHAK
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A substance which regulates immune-checkpoints for use as a medicament for treatment of a tumor of a patient wherein the administration pattern of the medicament comprises administering a therapeutically effective amount of the substance to the tumor, in one or more sessions, and implanting seeds (204) carrying radium-224 in the tumor for intratumoral alpha-emitter radiotherapy less than two weeks from administering the substance.