Use of therapeutic compositions for the treatment of patients with tumors of epithelial origin
The present invention relates to the branches of Biotechnology and Medicine. It describes the use of therapeutic compositions comprising a compound that blocks epidermal growth factor and an antibody that blocks the PD-1/PD-1 ligand signaling pathway in the treatment of tumors of epithelial origin,...
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| creator | SAAVEDRA HERNANDEZ, DANAY EVANS, RACHEL REID, MARY MESA PARDILLO, CIRCE LEON MONZON, KALET MAZORRA HERRERA, ZAIMA JOHNSON, CANDACE MUHITCH, JASON LEE, KELVIN LORENZO-LUACES ALVAREZ, PATRICIA DY, GRACE HUTSON, ALAN CROMBET RAMOS, TANIA |
| description | The present invention relates to the branches of Biotechnology and Medicine. It describes the use of therapeutic compositions comprising a compound that blocks epidermal growth factor and an antibody that blocks the PD-1/PD-1 ligand signaling pathway in the treatment of tumors of epithelial origin, particularly those that express the native form for human KRAS protein. In patients with cancer of epithelial origin expressing native KRAS treated with said therapeutic compositions, an increase in their survival was observed. |
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It describes the use of therapeutic compositions comprising a compound that blocks epidermal growth factor and an antibody that blocks the PD-1/PD-1 ligand signaling pathway in the treatment of tumors of epithelial origin, particularly those that express the native form for human KRAS protein. In patients with cancer of epithelial origin expressing native KRAS treated with said therapeutic compositions, an increase in their survival was observed.</description><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230401&DB=EPODOC&CC=TW&NR=202313106A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230401&DB=EPODOC&CC=TW&NR=202313106A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SAAVEDRA HERNANDEZ, DANAY</creatorcontrib><creatorcontrib>EVANS, RACHEL</creatorcontrib><creatorcontrib>REID, MARY</creatorcontrib><creatorcontrib>MESA PARDILLO, CIRCE</creatorcontrib><creatorcontrib>LEON MONZON, KALET</creatorcontrib><creatorcontrib>MAZORRA HERRERA, ZAIMA</creatorcontrib><creatorcontrib>JOHNSON, CANDACE</creatorcontrib><creatorcontrib>MUHITCH, JASON</creatorcontrib><creatorcontrib>LEE, KELVIN</creatorcontrib><creatorcontrib>LORENZO-LUACES ALVAREZ, PATRICIA</creatorcontrib><creatorcontrib>DY, GRACE</creatorcontrib><creatorcontrib>HUTSON, ALAN</creatorcontrib><creatorcontrib>CROMBET RAMOS, TANIA</creatorcontrib><title>Use of therapeutic compositions for the treatment of patients with tumors of epithelial origin</title><description>The present invention relates to the branches of Biotechnology and Medicine. 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It describes the use of therapeutic compositions comprising a compound that blocks epidermal growth factor and an antibody that blocks the PD-1/PD-1 ligand signaling pathway in the treatment of tumors of epithelial origin, particularly those that express the native form for human KRAS protein. In patients with cancer of epithelial origin expressing native KRAS treated with said therapeutic compositions, an increase in their survival was observed.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Use of therapeutic compositions for the treatment of patients with tumors of epithelial origin |
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