JAK2 inhibitors and methods of use thereof

JAK2 inhibitors and methods of use thereof

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of JAK2 enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders a...

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Hauptverfasser: TAYLOR, ALEXANDER M, MCLEAN, THOMAS H, FRIDRICH, CARY GRIFFIN, THOMSON, CHRISTOPHER, KURUKULASURIYA, RAVI, SWETT, REBECCA JANE, EVANS, CATHERINE A, BOEZIO, ALESSANDRO, DIPIETRO, LUCIAN V, MADEC, AMAEL
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Sprache:chi ; eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator TAYLOR, ALEXANDER M
MCLEAN, THOMAS H
FRIDRICH, CARY GRIFFIN
THOMSON, CHRISTOPHER
KURUKULASURIYA, RAVI
SWETT, REBECCA JANE
EVANS, CATHERINE A
BOEZIO, ALESSANDRO
DIPIETRO, LUCIAN V
MADEC, AMAEL
description The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of JAK2 enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with JAK2 signaling with the compounds and compositions of the disclosure.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title JAK2 inhibitors and methods of use thereof
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