Anti-CD48 antibodies, antibody drug conjugates, and uses thereof

Anti-CD48 antibodies, antibody drug conjugates, and uses thereof

Disclosed herein are antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof that bind human CD48. Also disclosed are pharmaceutical compositions comprising the antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof; and methods of making and...

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Bibliographische Detailangaben
Hauptverfasser: D'ALESSIO, JOSEPH ANTHONY, MUNDT, CORNELIA ANNE, WINKELBACH, KATHARINA, SCHWEIGHOFFER, TAMAS, NEWCOMBE, RICHARD VAUGHAN, KLINTER, CLAUDIA JUDITH
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed herein are antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof that bind human CD48. Also disclosed are pharmaceutical compositions comprising the antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof; and methods of making and using such pharmaceutical compositions for treating cancer in a patient in need of treatment.