(Aza)benzothiazolyl substituted pyrazole compounds

(Aza)benzothiazolyl substituted pyrazole compounds

This application includes a compound of Formula I or a pharmaceutically acceptable salt thereof; wherein the variables R1a, R1b, R2, R3, X, Y and Z are as defined herein, pharmaceutical compositions comprising the compounds of Formula I and methods of treatment comprising administering to a patient...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CABRAL, SHAWN, LAVERGNE, SOPHIE YVETTE, FENSOME, ANDREW, KORCZYNSKA, MAGDALENA, SHAVNYA, ANDRE, WISNIEWSKA, HANNA MARIA, WANG, TAO, CANTERBURY, DANIEL PAUL, PIOTROWSKI, DAVID WALTER, LONDREGAN, ALLYN TIMOTHY, DOW, ROBERT LEE, MASCITTI, VINCENT, TU, MEIHUA MIKE
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This application includes a compound of Formula I or a pharmaceutically acceptable salt thereof; wherein the variables R1a, R1b, R2, R3, X, Y and Z are as defined herein, pharmaceutical compositions comprising the compounds of Formula I and methods of treatment comprising administering to a patient in need thereof a compound of Formula I for the treatment of transthyretin amyloidosis and diseases related thereto.