Molecules with solubility tag and related methods

The present disclosure relates to molecules with solubility tag and to methods for increasing the solubility of a molecule. Moreover, the present disclosure relates to antibody-drug conjugates with solubility tag, methods and compounds for preparing such antibody-drug conjugates, methods for increas...

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Bibliographische Detailangaben
Hauptverfasser: RICHTER-SANDER, ULRIKE, KORPUS, CHRISTOPH, VON HAGEN, JOERG, KELLY, SVEN, DEUTSCH, CARL, CRASSIER, HELENE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present disclosure relates to molecules with solubility tag and to methods for increasing the solubility of a molecule. Moreover, the present disclosure relates to antibody-drug conjugates with solubility tag, methods and compounds for preparing such antibody-drug conjugates, methods for increasing the solubility of antibody-drug conjugates, antibody-drug conjugates prepared by such methods, as well as the use of such antibody-drug conjugates in medical treatment.