BRAF degraders

Present invention provides compounds that cause specifically the degradation of BRAF. The present compounds are useful for the treatment of various cancers.

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Bibliographische Detailangaben
Hauptverfasser:	JACKSON, KATRINA L, RIEMER, CLAUS, NASVESCHUK, CHRISTOPHER G, YU, ROBERT T, PETTAZZONI, PIERGIORGIO FRANCESCO TOMMASO, YAP, JEREMY L, DOLENTE, COSIMO, GARZA, VICTORIA, DUPLESSIS, MARTIN, LIANG, YAN-KE, HEWINGS, DAVID STEPHEN, MOUSTAKIM, MOSES, GOOD, ANDREW CHARLES, HUNZIKER, DANIEL, O'SHEA, MORGAN WELZEL, VEITS, GESINE KERSTIN, FITZGERALD, MARK E, KUHN, BERND, RICKLIN, FABIENNE, WICHMANN, JUERGEN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Present invention provides compounds that cause specifically the degradation of BRAF. The present compounds are useful for the treatment of various cancers.