Efficient peptide condensation method for difficult sequences

The present invention allows condensation reaction to proceed efficiently even when an amino acid having a high steric hindrance is included and allows a desired peptide compound to be obtained with high yield and high purity, as a result of using less additives relative to the amino acid or peptide...

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Hauptverfasser: WADAMOTO, MANABU, SHIINA, JUNICHI, IWASAKI, KOTARO
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creator WADAMOTO, MANABU
SHIINA, JUNICHI
IWASAKI, KOTARO
description The present invention allows condensation reaction to proceed efficiently even when an amino acid having a high steric hindrance is included and allows a desired peptide compound to be obtained with high yield and high purity, as a result of using less additives relative to the amino acid or peptide added to the N terminus.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title Efficient peptide condensation method for difficult sequences
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