Efficient peptide condensation method for difficult sequences

The present invention allows condensation reaction to proceed efficiently even when an amino acid having a high steric hindrance is included and allows a desired peptide compound to be obtained with high yield and high purity, as a result of using less additives relative to the amino acid or peptide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WADAMOTO, MANABU, SHIINA, JUNICHI, IWASAKI, KOTARO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention allows condensation reaction to proceed efficiently even when an amino acid having a high steric hindrance is included and allows a desired peptide compound to be obtained with high yield and high purity, as a result of using less additives relative to the amino acid or peptide added to the N terminus.