Fc variant and preparation thereof

The present invention relates to Fc variant protein and preparation thereof. Said Fc variant has altered binding affinity towards FcRn. Fc variant prepared according to the current invention can be used for making FcRn antagonist composition or can be used for making an Fc variant containing drug or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SHARMA, VIBHUTI, SONI, SWAGAT, PATEL, HEENA, PANDYA, HARDIK, SHAH, ANUSHREE, PATEL, CHIRAG, MENDIRATTA, SANJEEV KUMAR, SINGH, ARUN KUMAR, KASERA, RAMKRASHAN, VYAS, NARAYANI, PARIKH, AASHINI, HANDA, SATISH, KALITA, PANKAJ
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to Fc variant protein and preparation thereof. Said Fc variant has altered binding affinity towards FcRn. Fc variant prepared according to the current invention can be used for making FcRn antagonist composition or can be used for making an Fc variant containing drug or molecule with altered effector function.