Inhibitors of cysteine proteases and methods of use thereof

The disclosure provides compounds with warheads and their use in treating medical diseases or disorders, such as viral infections. Pharmaceutical compositions and methods of making various compounds with warheads are provided. The compounds are contemplated to inhibit proteases, such as the 3C, CL-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LOPATIN, URI, KEUNG, WALTER, ARNOLD, LEE D
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The disclosure provides compounds with warheads and their use in treating medical diseases or disorders, such as viral infections. Pharmaceutical compositions and methods of making various compounds with warheads are provided. The compounds are contemplated to inhibit proteases, such as the 3C, CL- or 3CL-like protease.