Composition containing palonosetron capable of being prepared in high concentration and for long-term preservation

The subject of the present invention is to provide a novel palonosetron composition. The composition of the present invention contains palonosetron (palonosetron hydrochloride or the like) and citric acid (citric acid, citrate or the like). The concentration of palonosetron is above 0.2 mg/mL in ter...

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Bibliographische Detailangaben
Hauptverfasser: YOSHIOKA, YU, TAIRA, HIKARU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The subject of the present invention is to provide a novel palonosetron composition. The composition of the present invention contains palonosetron (palonosetron hydrochloride or the like) and citric acid (citric acid, citrate or the like). The concentration of palonosetron is above 0.2 mg/mL in terms of palonosetron, the concentration of citric acid is below 8.5 mg/mL, and/or the ratio of citric acid relative to one mass parts of palonosetron is below 30 mass parts.