6-(fluoroalkyl)-3,4-dihydro-2h-pyran-5-carboxylic acid ester derivative, method for producing derivative, method for producing 2-(fluoroalkyl)nicotinic acid ester derivative, and method for producing 2-(fluoroalkyl)nicotinic acid derivative

The present invention provides: a 6-(fluoroalkyl)-3,4-dihydro-2H-pyran-5-carboxylic acid ester derivative represented by a specific formula (3); a method for producing the same; a method for producing a 2-(fluoroalkyl) nicotinic acid derivative which is represented by a specific formula (5), and is...

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Hauptverfasser: MORITA, MOTOAKI, HIROKI, HIDEKATSU, OOHASHI, TAKUMI, SUNAGAWA, SHO, OHNO, RYUTA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention provides: a 6-(fluoroalkyl)-3,4-dihydro-2H-pyran-5-carboxylic acid ester derivative represented by a specific formula (3); a method for producing the same; a method for producing a 2-(fluoroalkyl) nicotinic acid derivative which is represented by a specific formula (5), and is characterized in that the 6-(fluoroalkyl)-3,4-dihydro-2H-pyran-5-carboxylic acid ester derivative is reacted with an ammonium compound or ammonia, or is reacted with a base, an ammonium compound or ammonia, or after treating with acid or Lewis acid, is reacted with an ammonium compound or ammonia; and a method for producing an intermediate of the 2-(fluoroalkyl)nicotinic acid derivative.