[beta]-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same

A compound represented by Formula (I), a pharmaceutically acceptable salt or ester, hydrate, solvate or crystalline form thereof is provided: Formula (I). The compound represented by Formula (I) is a [beta]-amino acid derivative, and in Formula (I): X is a single bond or O; Y is NH or C=O; Z is C=O,...

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Hauptverfasser:	FU, CHIH-WEI, CHEN, YI-HSUN, HUNG, CHIU-LIEN, LIU, CHIH-PENG, TU, CHIA-MU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	FU, CHIH-WEI CHEN, YI-HSUN HUNG, CHIU-LIEN LIU, CHIH-PENG TU, CHIA-MU
description	A compound represented by Formula (I), a pharmaceutically acceptable salt or ester, hydrate, solvate or crystalline form thereof is provided: Formula (I). The compound represented by Formula (I) is a [beta]-amino acid derivative, and in Formula (I): X is a single bond or O; Y is NH or C=O; Z is C=O, C=S, NH,, or; W is C or N; A is a single bond, O, OH, OCH2, a heterocycle or N3; R1 is H or F; R2 is H, F, OH, CF3, CH2OH, CHO or; R3 is H; n is 0 or 1; and m is 0 or 1.
format	Patent
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The compound represented by Formula (I) is a [beta]-amino acid derivative, and in Formula (I): X is a single bond or O; Y is NH or C=O; Z is C=O, C=S, NH,, or; W is C or N; A is a single bond, O, OH, OCH2, a heterocycle or N3; R1 is H or F; R2 is H, F, OH, CF3, CH2OH, CHO or; R3 is H; n is 0 or 1; and m is 0 or 1.</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210716&DB=EPODOC&CC=TW&NR=202126628A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210716&DB=EPODOC&CC=TW&NR=202126628A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FU, CHIH-WEI</creatorcontrib><creatorcontrib>CHEN, YI-HSUN</creatorcontrib><creatorcontrib>HUNG, CHIU-LIEN</creatorcontrib><creatorcontrib>LIU, CHIH-PENG</creatorcontrib><creatorcontrib>TU, CHIA-MU</creatorcontrib><title>[beta]-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same</title><description>A compound represented by Formula (I), a pharmaceutically acceptable salt or ester, hydrate, solvate or crystalline form thereof is provided: Formula (I). 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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	[beta]-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same
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