Systems and methods for detection and prevention of emergence of agitation

Disclosed in the present disclosure is a method, system and apparatus for diagnosing an impending agitation episode in a subject predisposed to agitation. The disclosed method includes monitoring one or more physiological signals of sympathetic nervous system activity in the subject using an automated sensoring device placed or mounted on the subject's skin surface; and identifying, via the processing of incoming data in the device, when the subject is about to have an agitation episode. The disclosure provides a solution for measuring the signs of an impending agitation event, and alerts the caregiver to treat the subject before the emergence of agitation and a suitable treatment thereof.