Anti-CD96 antibodies and methods of use thereof

The instant disclosure provides antibodies that specifically bind to CD96 (e.g., human CD96) and antagonize CD96 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies...

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Bibliographische Detailangaben
Hauptverfasser: BUSHELL, K. MARK, GOMBOS, RANDI BARBARA, RAMSAY, NICOLA ANNE, CHAND, DHAN SIDHARTHA, IGNATOVICH, OLGA, BRIEND, EMMANUEL CYRILLE PASCAL
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The instant disclosure provides antibodies that specifically bind to CD96 (e.g., human CD96) and antagonize CD96 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.