Conditional medium of mesenchymal stem cells and hyaluronate mixture and the use thereof

The present invention is directed to a conditional medium and the use thereof; wherein the conditional medium is prepared by the steps of contacting mesenchymal stem cells with hyaluronate mixture and then co-culturing the cells. The conditional medium is effective in repairing the damage of cells c...

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Bibliographische Detailangaben
Hauptverfasser: LIAO, KUAN-YA, WUTANG, BOUNG, CHIEN, CHIA-WEN, SHIH, HUNG-TA, HSUAN, CHANG-YO, LIN, WILLIE WEI-LI, LEE, YAN ZHANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention is directed to a conditional medium and the use thereof; wherein the conditional medium is prepared by the steps of contacting mesenchymal stem cells with hyaluronate mixture and then co-culturing the cells. The conditional medium is effective in repairing the damage of cells caused by oxidative stress, and increasing cell viability. The disclosure also provides a method of increasing the secretion of DKK-1 by mesenchymal stem cells.