Processes for preparing toll-like receptor modulator compounds

The present disclosure provides methods for preparing (R)-2-((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol or a salt thereof and related key intermediates.

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Hauptverfasser: WANG, XIANGHONG, ZHENG, ZE-HUA, AMBROSI, ANDREA, LEW, WILLARD, ASSELIN, SYLVIE M, AKTOUDIANAKIS, EVANGELOS, BADALOV, PAVEL R, REGENS, CHRISTOPHER S, METOBO, SAMUEL E, MISH, MICHAEL R, VIEIRA, TIAGO, PRITCHETT, BEAU P, WENDERSKI, TODD A, CHIN, GREGORY F, MERIT, JEFFREY E, BACHRACH, FLORENCE J, LATHROP, STEPHEN P, MACKMAN, RICHARD L, PYUN, HYUNG-JUNG, WEINSTEIN, ADAM B
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Sprache:chi ; eng
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creator WANG, XIANGHONG
ZHENG, ZE-HUA
AMBROSI, ANDREA
LEW, WILLARD
ASSELIN, SYLVIE M
AKTOUDIANAKIS, EVANGELOS
BADALOV, PAVEL R
REGENS, CHRISTOPHER S
METOBO, SAMUEL E
MISH, MICHAEL R
VIEIRA, TIAGO
PRITCHETT, BEAU P
WENDERSKI, TODD A
CHIN, GREGORY F
MERIT, JEFFREY E
BACHRACH, FLORENCE J
LATHROP, STEPHEN P
MACKMAN, RICHARD L
PYUN, HYUNG-JUNG
WEINSTEIN, ADAM B
description The present disclosure provides methods for preparing (R)-2-((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol or a salt thereof and related key intermediates.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Processes for preparing toll-like receptor modulator compounds
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