Processes for preparing toll-like receptor modulator compounds

Processes for preparing toll-like receptor modulator compounds

The present disclosure provides methods for preparing (R)-2-((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol or a salt thereof and related key intermediates.

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Bibliographische Detailangaben
Hauptverfasser: WANG, XIANGHONG, ZHENG, ZE-HUA, AMBROSI, ANDREA, LEW, WILLARD, ASSELIN, SYLVIE M, AKTOUDIANAKIS, EVANGELOS, BADALOV, PAVEL R, REGENS, CHRISTOPHER S, METOBO, SAMUEL E, MISH, MICHAEL R, VIEIRA, TIAGO, PRITCHETT, BEAU P, WENDERSKI, TODD A, CHIN, GREGORY F, MERIT, JEFFREY E, BACHRACH, FLORENCE J, LATHROP, STEPHEN P, MACKMAN, RICHARD L, PYUN, HYUNG-JUNG, WEINSTEIN, ADAM B
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure provides methods for preparing (R)-2-((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol or a salt thereof and related key intermediates.