Recombinant vaccinia virus and methods of use thereof

The present disclosure provides a replication-competent, recombinant oncolytic vaccinia virus, compositions comprising the vaccinia virus, and use of the vaccinia virus or composition for inducing oncolysis in an individual having a tumor.

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Bibliographische Detailangaben
Hauptverfasser: MARURI AVIDAL, LILIANA, LIMSIRICHAI, PRAJIT, KIRN, DAVID H
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present disclosure provides a replication-competent, recombinant oncolytic vaccinia virus, compositions comprising the vaccinia virus, and use of the vaccinia virus or composition for inducing oncolysis in an individual having a tumor.