Arylsulfonylpyrolecarboxamide derivatives as Kv3 potassium channel activators

The present invention provides novel compounds which activate the Kv3 potassium channels. The compounds have the structure. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and use of the compounds to treat disorders responsive to the activation...

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Bibliographische Detailangaben
Hauptverfasser:	RASMUSSEN, LARS KYHN, FLEMING, PAUL ROBERT, YU, WAN-WAN, SAMS, ANETTE GRAVEN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides novel compounds which activate the Kv3 potassium channels. The compounds have the structure. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and use of the compounds to treat disorders responsive to the activation of Kv3 potassium channels.